Harnessing the lymph node microenvironment
نویسندگان
چکیده
منابع مشابه
Changes in the lymph node microenvironment induced by oncostatin M.
Oncostatin M (OM) transforms the lymph node (LN) into a "super lymphoid organ" with 2 striking features: massive thymus-independent T-cell development and major expansion of the memory T-cell pool. We report that T-cell development in the LckOM LN is regulated by a cyclooxygenase-2 (COX-2)-dependent neoangiogenesis involving high endothelial venules (HEVs). That LN HEVs are particularlyrich in ...
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ژورنال
عنوان ژورنال: Current Opinion in Organ Transplantation
سال: 2018
ISSN: 1087-2418
DOI: 10.1097/mot.0000000000000488